The Clue Leonardo Da Vinci's "Mona ____"
The Answer LISA
The answer to the crossword clue is "LISA" because Leonardo Da Vinci painted the famous artwork called "Mona Lisa." This painting is one of the most recognized pieces of art in the world. The name "Mona" means "Lady" in Italian, so "Mona Lisa" translates to "Lady Lisa." This connection makes "LISA" the perfect fit for the clue.