The Clue ___ hours: say 4 am
The Answer WEE
The answer "WEE" fits the clue because "wee hours" refers to the early morning hours, typically around midnight to dawn. Saying 4 AM is often considered part of the "wee hours." The term is commonly used to describe a time when most people are still asleep. Thus, "wee" is a perfect match for the clue.